In 2005, 120 of the finalists from previous years returned to BJU as freshmen.The university's nursing major is approved by the South Carolina State Board of Nursing, and a BJU graduate with a BSN is eligible to take the National Council Licensure Examination to become a registered nurse.

Many of these students go on to a seminary after completing their undergraduate degree.

Others take ministry positions straight from college, and rising juniors participate in a church internship program to prepare them for the pastoral ministry.

In 1944, Jones wrote to John Walvoord of Dallas Theological Seminary that while the university had "no objection to educational work highly standardized….

We, however, cannot conscientiously let some group of educational experts or some committee of experts who may have a behavioristic or atheistic slant on education control or even influence the administrative policies of our college." Early in the history of the college, there had been some hesitancy on the part of other institutions to accept BJU credits at face value, but by the 1960s, BJU alumni were being accepted by most of the major graduate and professional schools in the United States.

Though he had served as Acting President as early as 1934, Jones' son, Bob Jones, Jr.

officially became the school's second president in 1947 just before the college moved to Greenville, South Carolina, and became Bob Jones University.

grew increasingly concerned about the secularization of higher education and the influence of religious liberalism in denominational colleges.

Children of church members were attending college, only to reject the faith of their parents.

In 1995 there were 1,290 BJU graduates serving as senior or associate pastors in churches across the United States.

The university requires use of the King James Version (KJV) of the Bible in its services and classrooms, but it does not hold that the KJV is the only acceptable English translation or that it has the same authority as the original Hebrew and Greek manuscripts.

Undoubtedly helpful was that some of the university's strongest programs were in the areas of music, speech, and art, disciplines in which ability could be measured by audition or portfolio rather than through paper qualifications.